Francois Meyer graduated (magna cum laude) from Ecole Nationale Supérieure d'Informatique et de Mathématiques Appliquées, Grenoble, in 1987, with a M.S. in applied mathematics and computer science. Meyer received a Ph.D. in electrical engineering from INRIA, France, in 1993. His Ph.D. advisor was Dr. Patrick Bouthemy.

During his military service, he worked on the thermonuclear fusion program of the French Nuclear Energy Agency. He then worked as a software engineer in the department of radiotherapy of the Institute Gustave Roussy. He later worked at Safran on the qualification of the digital control unit of the M88 engine for the Rafale fighter aircraft.

Francois Meyer is currently Professor in the department of Applied Mathematics, University of Colorado, Boulder. He was an Assistant Professor (1999-2005), Associate Professor (2005-2013), and Professor (2013-2019) in the department of Electrical, Computer, and Energy Engineering at the University of Colorado, Boulder.

He had previously been an Assistant Professor at Yale University (1997-1999), a Visiting Professor at the Institute Henri Poincaré, Paris (1999), a Senior Fellow at the Institute of Pure and Applied Mathematics, (UCLA) (2004), a Visiting Research Scholar at Princeton University (2007), and a Visiting Scholar ICERM, Brown University (2014), a Visiting Professor (fellowship Jean d'Alembert) at INRIA-Saclay and NeuroSpin (2017).